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Something broken with seqinfo in latest rtracklayer update? #3

@alexwskh

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@alexwskh

I for the life of me cannot get around this issue when trying to renormalize my bigwigs to each other. I also fail during the runLILY script when it has to handle bigwigs. This did work two months ago...

total_densities = apply(files_info,1,get_peaks_density_commonPeaks)
Error: unable to find an inherited method for function ‘seqinfo’ for signature ‘x = "BigWigFile"’

R version 4.5.1 (2025-06-13)
Platform: x86_64-pc-linux-gnu
Running under: Ubuntu 24.04.3 LTS

Matrix products: default
BLAS:   /usr/lib/x86_64-linux-gnu/blas/libblas.so.3.12.0 
LAPACK: /usr/lib/x86_64-linux-gnu/lapack/liblapack.so.3.12.0  LAPACK version 3.12.0

locale:
 [1] LC_CTYPE=en_US.UTF-8       LC_NUMERIC=C               LC_TIME=en_US.UTF-8        LC_COLLATE=en_US.UTF-8     LC_MONETARY=en_US.UTF-8   
 [6] LC_MESSAGES=en_US.UTF-8    LC_PAPER=en_US.UTF-8       LC_NAME=C                  LC_ADDRESS=C               LC_TELEPHONE=C            
[11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C       

time zone: America/Toronto
tzcode source: system (glibc)

attached base packages:
[1] stats4    stats     graphics  grDevices utils     datasets  methods   base     

other attached packages:
[1] rtracklayer_1.68.0   GenomicRanges_1.62.0 Seqinfo_1.0.0        IRanges_2.44.0       S4Vectors_0.48.0     BiocGenerics_0.56.0  generics_0.1.4      

loaded via a namespace (and not attached):
 [1] Matrix_1.7-3                jsonlite_2.0.0              compiler_4.5.1              rjson_0.2.23                crayon_1.5.3               
 [6] SummarizedExperiment_1.40.0 Biobase_2.70.0              Rsamtools_2.24.1            bitops_1.0-9                Biostrings_2.78.0          
[11] GenomicAlignments_1.44.0    parallel_4.5.1              BiocParallel_1.42.2         yaml_2.3.12                 lattice_0.22-5             
[16] R6_2.6.1                    XVector_0.50.0              S4Arrays_1.10.0             curl_7.0.0                  GenomeInfoDb_1.44.3        
[21] XML_3.99-0.20               DelayedArray_0.36.0         MatrixGenerics_1.22.0       GenomeInfoDbData_1.2.14     SparseArray_1.10.3         
[26] grid_4.5.1                  rstudioapi_0.17.1           codetools_0.2-20            abind_1.4-8                 RCurl_1.98-1.17            
[31] restfulr_0.0.16             httr_1.4.7                  matrixStats_1.5.0           tools_4.5.1                 BiocIO_1.18.0              
[36] UCSC.utils_1.4.0           

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