Hi folks,
Not sure how it happened, but a site ended with two different Tab items with the same Placeholder Name were created at the /sitecore/client/Applications/ExperienceProfile/Contact/PageSettings/Tabs folder.
This fact caused the Process method of Initialize class failed and blocked the entire site. The following image is a screenshot of the error I got when I try to load the home page of the site.

I created this issue to track the problem and I will create a branch and a pull request with the solution.
A.