As per title, I'm not sure which requirement is causing the problem, but I suspect it's ephem.
When trying to run operateShutters.py all you get is an Illegal Operation message, probably because a newer version of one of the dependencies has native code built for a newer instruction set.
I've found pinning the versions in requirements.txt fixes this, I suggest that either the versions are pinned in this repo or an alternative requirements.pizero.txt be added containing something like this (my last known good versions):
ephem==4.0.0.2
configparser==5.0.2
Flask==2.0.1
paho-mqtt==1.5.1
pigpio==1.78