diff --git a/.dep-versions b/.dep-versions
index f7e68582d9..88f6c9ebf3 100644
--- a/.dep-versions
+++ b/.dep-versions
@@ -10,7 +10,7 @@ enzyme=v0.0.203
 
 # For a custom PL version, update the package version here and at
 # 'doc/requirements.txt'
-pennylane=0.44.0-dev50
+pennylane=0.44.0.dev54
 
 # For a custom LQ/LK version, update the package version here and at
 # 'doc/requirements.txt'
diff --git a/frontend/catalyst/device/decomposition.py b/frontend/catalyst/device/decomposition.py
index 22c66deac3..bddf79cf07 100644
--- a/frontend/catalyst/device/decomposition.py
+++ b/frontend/catalyst/device/decomposition.py
@@ -42,6 +42,7 @@
     is_controllable,
     is_differentiable,
     is_invertible,
+    is_quantum_gate,
     is_supported,
 )
 from catalyst.jax_tracer import HybridOpRegion, has_nested_tapes
@@ -227,7 +228,7 @@ def catalyst_acceptance(
         if match and is_controllable(op.base, capabilities):
             return match
 
-    elif is_supported(op, capabilities):
+    elif is_supported(op, capabilities) and is_quantum_gate(op):
         return op.name
 
     return None
diff --git a/frontend/catalyst/device/op_support.py b/frontend/catalyst/device/op_support.py
index f86f0cc2c9..099d19d7fa 100644
--- a/frontend/catalyst/device/op_support.py
+++ b/frontend/catalyst/device/op_support.py
@@ -40,6 +40,10 @@ def is_supported(op: Operator, capabilities: DeviceCapabilities) -> bool:
     """Check whether an operation is supported by the device."""
     return op.name in capabilities.operations
 
+def is_quantum_gate(op: Operator) -> bool:
+    """Check whether an operation is a quantum gate."""
+    return isinstance(op, qml.operation.Gate)
+    # and isinstance(op, qml.operation.DynamicGate)
 
 def _is_grad_recipe_same_as_catalyst(op):
     """Checks that the grad_recipe for the op matches the hard coded one in Catalyst."""
diff --git a/frontend/catalyst/device/qjit_device.py b/frontend/catalyst/device/qjit_device.py
index 77aa57e5aa..c4da627ce4 100644
--- a/frontend/catalyst/device/qjit_device.py
+++ b/frontend/catalyst/device/qjit_device.py
@@ -60,44 +60,6 @@
 logger = logging.getLogger(__name__)
 logger.addHandler(logging.NullHandler())
 
-RUNTIME_OPERATIONS = [
-    "CNOT",
-    "ControlledPhaseShift",
-    "CRot",
-    "CRX",
-    "CRY",
-    "CRZ",
-    "CSWAP",
-    "CY",
-    "CZ",
-    "Hadamard",
-    "Identity",
-    "IsingXX",
-    "IsingXY",
-    "IsingYY",
-    "IsingZZ",
-    "SingleExcitation",
-    "DoubleExcitation",
-    "ISWAP",
-    "MultiRZ",
-    "PauliX",
-    "PauliY",
-    "PauliZ",
-    "PCPhase",
-    "PhaseShift",
-    "PSWAP",
-    "QubitUnitary",
-    "Rot",
-    "RX",
-    "RY",
-    "RZ",
-    "S",
-    "SWAP",
-    "T",
-    "Toffoli",
-    "GlobalPhase",
-]
-
 RUNTIME_OBSERVABLES = [
     "Identity",
     "PauliX",
@@ -113,12 +75,6 @@
 
 RUNTIME_MPS = ["ExpectationMP", "SampleMP", "VarianceMP", "CountsMP", "StateMP", "ProbabilityMP"]
 
-# The runtime interface does not care about specific gate properties, so set them all to True.
-RUNTIME_OPERATIONS = {
-    op: OperatorProperties(invertible=True, controllable=True, differentiable=True)
-    for op in RUNTIME_OPERATIONS
-}
-
 RUNTIME_OBSERVABLES = {
     obs: OperatorProperties(invertible=True, controllable=True, differentiable=True)
     for obs in RUNTIME_OBSERVABLES
@@ -227,9 +183,8 @@ def get_qjit_device_capabilities(target_capabilities: DeviceCapabilities) -> Dev
     qjit_capabilities = deepcopy(target_capabilities)
 
     # Intersection of gates and observables supported by the device and by Catalyst runtime.
-    qjit_capabilities.operations = intersect_operations(
-        target_capabilities.operations, RUNTIME_OPERATIONS
-    )
+    qjit_capabilities.operations = target_capabilities.operations
+
     qjit_capabilities.observables = intersect_operations(
         target_capabilities.observables, RUNTIME_OBSERVABLES
     )
diff --git a/frontend/catalyst/from_plxpr/qfunc_interpreter.py b/frontend/catalyst/from_plxpr/qfunc_interpreter.py
index 59c6e516c7..9ef6f66224 100644
--- a/frontend/catalyst/from_plxpr/qfunc_interpreter.py
+++ b/frontend/catalyst/from_plxpr/qfunc_interpreter.py
@@ -36,6 +36,7 @@
 from pennylane.ftqc.primitives import measure_in_basis_prim as plxpr_measure_in_basis_prim
 from pennylane.measurements import CountsMP
 
+from catalyst.device.op_support import is_quantum_gate
 from catalyst.jax_extras import jaxpr_pad_consts
 from catalyst.jax_primitives import (
     AbstractQbit,
@@ -183,7 +184,11 @@ def interpret_operation(self, op, is_adjoint=False, control_values=(), control_w
         if (fn := _special_op_bind_call.get(type(op))) is not None:
             bind_fn = partial(fn, hyperparameters=op.hyperparameters)
         else:
-            bind_fn = qinst_p.bind
+            if not is_quantum_gate(op):
+                raise CompileError(
+                    f"Operation {op.name} with hyperparameters {list(op.hyperparameters.keys())} "
+                    "is not compatible with quantum instructions."
+                )
 
         out_qubits = bind_fn(
             *[*in_qubits, *op.data, *in_ctrl_qubits, *control_values],