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This repository was archived by the owner on Jan 22, 2025. It is now read-only.
This repository was archived by the owner on Jan 22, 2025. It is now read-only.

Features of priority for the next release #14

@burtonrj

Description

@burtonrj
  • User should be able to load a CSV file or pass a pandas dataframe to add_new_sample method of Experiment when populating an experiment with data
  • Often the optimal parameters for a clustering algorithm used to 'gate' single cell data in two-dimensions differ from one sample to the next, it would be great to provide the option to perform hyperparameter search - parameters chosen that minimise the Hausdorff distance between newly clustered populations and the populations originally defined
  • Improve coverage of unit tests
  • Generate a new class structure similar to CellClassifier but inspired by https://www.pnas.org/content/117/35/21373 - should be able to merge the data from multiple subjects using create_ref_sample, label single cells with their origin, and train a classifier to predict the origin of a single cell (i.e. did it originate from a diseased individual), then inspect the model for populations that contribute to that prediction
  • Port FlowAI for cleaning data prior to entry with add_new_sample

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