We have some pages that return a list of every registration in a session, with information about the registrants. These are slow to render, perhaps because they're database-expensive or because we're doing something dumb.
Anyway, the URLs for these return 404s from Nginx. I think that Django is busily trying to produce the data but Nginx gets tired of waiting and sends the user a 404.
See:
http://knowledgecommonsdc.org/classes/staff/registrations/session/1209/