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+# Model Code: Ca²⁺ current vs. Ca²⁺ channel cooperativity
+
+[CalC Download](http://web.njit.edu/%7Ematveev/calc.html) | [CalC Manual](http://web.njit.edu/%7Ematveev/calc/manual.html) | [CalC Scripts](http://web.njit.edu/%7Ematveev/calc/scripts.html) | [CalC Publications](http://web.njit.edu/%7Ematveev/calc/calc_pub.html) | [Victor's Homepage](http://web.njit.edu/%7Ematveev/)
+
+
+The scripts following below reproduce the simulation results presented in the manuscript:
+
+
+Victor V. Matveev, Richard Bertram and Arthur Sherman (2009)  
+**Ca²⁺ current vs. Ca²⁺ channel cooperativity of exocytosis**
+*Journal of Neuroscience*, **29**(39): 12196-12209.  
+[Abstract](http://www.jneurosci.org/cgi/content/abstract/29/39/12196) | [Full Text](http://www.jneurosci.org/cgi/content/full/29/39/12196)
+
+----
+♦ [Fig1.par](http://web.njit.edu/%7Ematveev/Scripts/MvsN/Fig1.par)  
+This CalC script generates the first figure of the manuscript. It requires a single command-line parameter, the total buffer concentration (in μM) (e.g. run `calc Fig1.par 100`). The simulation produces an ASCII data file with five columns:  
+1. single-channel Ca²⁺ current (varied from 0.001 to 1 pA);  
+2. maximal release produced by a 1ms-long current pulse;  
+3. corresponding maximal [Ca²⁺] at release site, 30 nm from channel;  
+4. maximal volume-averaged [Ca²⁺];  
+5. time to peak release after simulation start.
+
+
+♦ [Fig1.m](http://web.njit.edu/%7Ematveev/Scripts/MvsN/Fig1.m)  
+A MATLAB m-file that generates Figure 1 using data produced by CalC script `Fig1.par` above.
+
+
+♦ [Fig7_8.par](http://web.njit.edu/%7Ematveev/Scripts/MvsN/Fig7_8.par)  
+This CalC script generates data for Figures 7 and 8 of the manuscript. The simulation produces an ASCII data file used by MATLAB script `Fig7_8.m` below.
+
+
+♦ [Fig7_8.m](http://web.njit.edu/%7Ematveev/Scripts/MvsN/Fig7_8.m)  
+A MATLAB m-file that generates Figures 7 and 8 using data produced by CalC script `Fig7_8.par` above.
+
+
+♦ [process2D.m](http://web.njit.edu/%7Ematveev/Scripts/MvsN/process2D.m)  
+A simple MATLAB data parsing script required by MATLAB m-files `Fig1.m` and `Fig7_8.m`.
+
+
+---
+
+Supported in part by the **National Science Foundation** grant **DMS 0817703** to Victor Matveev
+
+
+Victor Matveev  
+This server is running a [Redhat](http://www.redhat.com/) distribution of [Linux](http://www.linux.org/).  
+
+---
+Last modified: January 8, 2010  
+Converted README to Markdown: June 2, 2025