Added New AUC Pk Parameters#486
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PavanLomati merged 5 commits intohumanpred:mainfrom Dec 3, 2025
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Description: Calculate oral or IV clearance. Function name: pk.calc.cl • Existing parameters: cl.last, cl.all, cl.obs, cl.pred • New parameters added: cl.int.all, cl.int.inf.obs, cl.int.inf.pred, cl.int.last, cl.iv.all, cl.iv.last, cl.iv.obs, cl.iv.pred, cl.ivint.all, cl.ivint.last, cl.sparse.last ________________________________________ 2. Elimination Rate Constant (Kel) Description: Calculate the elimination rate constant (Kel). Function name: pk.calc.kel • Existing parameters: kel.last, kel.obs, kel.pred, kel.iv.last, kel.iv.obs, kel.iv.pred • New parameters added: kel.all, kel.int.all, kel.int.inf.obs, kel.int.inf.pred, kel.int.last, kel.iv.all, kel.ivint.all, kel.ivint.last, kel.sparse.last ________________________________________ 3. Mean Residence Time (MRT) — Oral or General Description: Calculate the mean residence time (MRT) for single-dose or linear multiple-dose data. Function name: pk.calc.mrt • Existing parameters: mrt.last, mrt.obs, mrt.pred • New parameters added: mrt.all, mrt.int.all, mrt.int.inf.obs, mrt.int.inf.pred, mrt.int.last, mrt.sparse.last ________________________________________ 4. Mean Residence Time (MRT) — IV Infusion Description: MRT calculation specifically for IV infusion. Function name: pk.calc.mrt.iv • Existing parameters: mrt.iv.last, mrt.iv.obs, mrt.iv.pred • New parameters added: mrt.iv.all, mrt.ivint.all, mrt.ivint.last ________________________________________ 5. Steady-State Volume of Distribution (Vss) Description: Calculate the steady-state volume of distribution (Vss). Function name: pk.calc.vss • Existing parameters: vss.iv.last, vss.iv.obs, vss.iv.pred, vss.last, vss.md.obs, vss.md.pred, vss.obs, vss.pred • New parameters added: vss.all, vss.int.all, vss.int.inf.obs, vss.int.inf.pred, vss.int.last, vss.iv.all, vss.ivint.all, vss.ivint.last, vss.sparse.last ________________________________________ 6. Terminal Volume of Distribution (Vz) Description: Calculate the terminal volume of distribution (Vz). Function name: pk.calc.vz • Existing parameters: vz.obs, vz.pred • New parameters added: vz.all, vz.int.all, vz.int.inf.obs, vz.int.inf.pred, vz.int.last, vz.iv.all, vz.iv.last, vz.iv.obs, vz.iv.pred, vz.ivint.all, vz.ivint.last, vz.last; vz.sparse.last
- Changed unit.type to unit_type (correct parameter name) - Added sparse=TRUE for sparse data parameters
…ucivinf.obs and aucivinf.pred
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Description: Calculate oral or IV clearance.
Function name: pk.calc.cl
• Existing parameters:
cl.last, cl.all, cl.obs, cl.pred
• New parameters added:
cl.int.all, cl.int.inf.obs, cl.int.inf.pred, cl.int.last, cl.iv.all, cl.iv.last, cl.iv.obs, cl.iv.pred,
cl.ivint.all, cl.ivint.last,
cl.sparse.last
• Existing parameters:
kel.last, kel.obs, kel.pred,
kel.iv.last, kel.iv.obs, kel.iv.pred
• New parameters added:
kel.all, kel.int.all, kel.int.inf.obs, kel.int.inf.pred, kel.int.last, kel.iv.all,
kel.ivint.all, kel.ivint.last,
kel.sparse.last
• Existing parameters:
mrt.last, mrt.obs, mrt.pred
• New parameters added:
mrt.all, mrt.int.all, mrt.int.inf.obs, mrt.int.inf.pred, mrt.int.last, mrt.sparse.last
• Existing parameters:
mrt.iv.last, mrt.iv.obs, mrt.iv.pred
• New parameters added:
mrt.iv.all,
mrt.ivint.all, mrt.ivint.last
• Existing parameters:
vss.iv.last, vss.iv.obs, vss.iv.pred,
vss.last,
vss.md.obs, vss.md.pred,
vss.obs, vss.pred
• New parameters added:
vss.all, vss.int.all, vss.int.inf.obs, vss.int.inf.pred, vss.int.last, vss.iv.all,
vss.ivint.all, vss.ivint.last,
vss.sparse.last
• Existing parameters:
vz.obs, vz.pred
• New parameters added:
vz.all, vz.int.all, vz.int.inf.obs, vz.int.inf.pred, vz.int.last, vz.iv.all, vz.iv.last, vz.iv.obs, vz.iv.pred,
vz.ivint.all, vz.ivint.last,
vz.last; vz.sparse.last