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karbalaei/README.md

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Hi there πŸ‘‹

I am a Senior Bioinformatics Scientist at Johns Hopkins Medicine with over 9 years of experience in Genomic Data Science.

I specialize in Multi-omics and Single-cell Genomics, leveraging machine learning and statistical modeling to uncover the genetic mechanisms of neuropsychiatric disorders (Bipolar Disorder, Schizophrenia, MDD).


πŸ›  Languages & Infrastructure

Python R SQL SQL Bash

Linux AWS Docker Nextflow

🧬 Bioinformatics & ML Stack

scikit-learn TensorFlow

DESeq2 Seurat Scanpy GATK

snRNA-seq Multi-omics


πŸ”­ Current Research & Projects

  • Lithium Mechanism Study: Investigating gene expression changes in Bipolar Disorder patients using Bulk RNA-seq.
  • BP vs. MDD: Examination mechanism differences in BP patients versus MDD patients.
  • GWAS Pipelines: Developing reproducible Nextflow pipelines for large-scale variant association.
  • Reproducibility: Establishing open-science standards for psychiatric genomics.

πŸ“š Publications & Impact

Google Scholar

πŸ“« Connect with Me

LinkedIn

Pinned Loading

  1. Lithium-exposure Lithium-exposure Public

    R

  2. MDD_BP MDD_BP Public

    R

  3. scRNA_seq scRNA_seq Public

    Details about how to do scRNA-seq

    Shell