This repository provides the ASCAT R package that can be used to infer tumour purity, ploidy and allele-specific copy number profiles.
ASCAT is described in detail in “Allele-specific copy number analysis of tumors” Van Loo et al. PNAS 107(39): 16910-5 (2010).
This repository also contains the code underlying additional publications: "Allele-specific multi-sample copy number segmentation" Ross, Haase, Van Loo, Markowetz. bioRxiv (2017).
For more information about ASCAT and other projects of our group, please visit our website.