Chen_lab_analysis

Overall AMP-AD analysis (limma pipeline)

• Disease status
• APOE4 carrier
• APOE4 dose

Candidate genes

• LDs related genes (limma pipeline summary)
  • diagnosis
  • diagnosis and sex
  • APOE dose
  • APOE dose and sex
  • APOE carrier
  • APOE carrier and sex
  • plot
• LDs related genes (ANOVA)
• LDs related genes (t-test)
• LDs related genes (braak stage)
• Chromogranin A (CgA)(CHGA in human genome)

Update log

11/15/2022:

• Update comprehensive DE analysis results using limma and DESeq2 pipeline
• Update simple DE analysis using t-test and ANOVA on candidate genes
• Update result summary of comprehensive DE analysis on candidate genes
• Update CGA analysis

11/22/2022:

• Update metadata, speecifically the tissue information of MSBB study
• Update limma result (with new analysis regarding APOE carrier/dose) after metadata updates
• Update limma result summary
• Update CGA analysis result